Projects

Time: 02.2021 - 12.2025

Goal(s): 
We combine the technologies of 3D printing of living materials and the synthetic biology approach of non-traditional yeasts to create a novel, targeted living catalyst immobilization platform for biorefining that converts various organic wastes into more valuable oleochemicals.
Result(s): 
The basic understanding of non-conventional yeast Rhodotorula toruloides was aquired. The knowledge can be used for microbial cell factory development for oleochemical production from low-value substrates. A hydrogel-based platform that allows yeast cells to stay metabolically active while immobilized in the 3D-printed matrix was developed. Conversion of substrates to products was slightly more efficient, opening possibilities for further studies.

Time: 11.2023 - 10.2024

Goal(s): 
The BIOCONNECT project aims to help create a more robust, integrated, and inclusive Baltic ecosystem/cluster for biotechnology innovation as one of the key ingredients for the present and future economic competitiveness of the region.
Result(s): 
Baltic biotech action plan will be published and a memorandum signed collectively by all Baltic states.

Media: Latvian Institute of Organic Synthesis; ECHAlliance

Time: 06.2022 - 06.2024

Goal(s): 
Demonstrated the efficiency of a novel biotechnological process on a pilot scale that converts wood industry residues (pre-treated sawdust) into healthy feed and nutritional supplements. A life cycle analysis was performed on the process, quantitatively demonstrating the benefits of a circular economy process and a platform was created for the efficient development of industrial biotechnology processes on various sustainable commodities such as food waste, food industry and agricultural by-products.
Result(s): 
Non-conventional yeast Rhodotorula toruloides was able to tolerate inhibitors present in wood hydrolysates and grow on short-chain fatty acids obtained from food waste. While growing, it produced intracellular microbial oils and carotenoids. Both oils and carotenoids can be extracted and used as a feed and food supplements.

Media: Facebook

Publications

Authors: Monteiro de Oliveira P, Pinheiro M.J, Sabedotti de Biaggi J, Tšitšerin A, Tammekivi E, Herodes K, Bonturi N, Lahtvee P. J
Issue: bioRxiv
Year: 2023
Authors: Bonturi N, Crucellob A, Carvalho Vianab A.J, Alves Miranda E
Issue: Process Biochemistry 57:16-25
Year: 2017